Medical Researches
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Based on 8 Researches
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
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Vitamin D aids back pain reliefAdult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience.
Significant relevance to treatment
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
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Effectiveness of combined treatmentsCombined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial.
Vitamin D's individual impact unclear
We explored how a combination of treatments, including a specific vitamin D supplement (Cholecalciferol), could help alleviate back pain in young people suffering from sciatica due to herniated discs. In this study, we looked at 128 patients divided into three groups. One group received a combination of rehabilitation therapy and daily supplements, while the second group only underwent rehabilitation. The third group was given supplements without the additional therapy.
Over a span of 60 days, we measured improvements in pain levels, disability, and quality of life using various rating scales. We found that the group receiving both rehabilitation and supplements saw significant improvements in pain and overall quality of life after 30 days. However, after two months, while they still had better outcomes in pain and quality of life compared to the other groups, the vitamin D's individual effect couldn’t be distinctly isolated.
Ultimately, our findings suggest that while vitamin D was part of an effective treatment plan that included other beneficial supplements, we cannot attribute all the improvements in back pain directly to vitamin D alone. This highlights the importance of comprehensive treatment approaches for conditions like sciatica.
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Vitamin D alleviates back painThe effectiveness of vitamin D3 supplementation in improving functional outcome of non-surgically treated symptomatic lumbar spinal stenosis: Randomized controlled clinical trial - Pilot study.
High relevance to query
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
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We examined the impact of vitamin D treatment on patients experiencing back pain related to celiac disease. In one noteworthy case, a 66-year-old man sought help for persistent back and knee pain. After thorough testing, he was diagnosed with celiac disease, alongside vitamin D deficiency and low bone mineral density due to osteomalacia.
The treatment plan included a gluten-free diet and supplementation with vitamin D and calcium. Remarkably, over a span of six months, the patient reported immense relief from symptoms, along with improvements in bone mineral density.
Our findings highlight a significant link between vitamin D supplementation and improvements in musculoskeletal symptoms, particularly for those struggling with celiac disease. While we note that this case does not allow us to make definitive conclusions about vitamin D's isolated effects on back pain, it certainly suggests potential benefits worth considering.
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